Therapeutic Nanomaterials by Mustafa O. Guler, Ayse B. Tekinay

By Mustafa O. Guler, Ayse B. Tekinay

Addressing a state-of-the-art, multidisciplinary box, this ebook studies nanomaterials and their biomedical purposes. It covers regeneration, implants, adhesives, and biosensors and techniques for extra effective treatment, analysis, and drug supply with using nanotechnology.

• Addresses the expanding call for for nanomedicine in a state-of-the-art, multidisciplinary field
• Introduces options, options, and necessities of constructing materials
• Discusses scorching issues in drug supply, equivalent to neural regeneration, cartilage regeneration, bone tissue regeneration, dental regeneration, biomedical imaging, tissue adhesives and biosensors
• Includes a bankruptcy approximately nanotoxicology to assist readers additional comprehend the biocompatability of nanomaterials

Show description

By Mustafa O. Guler, Ayse B. Tekinay

Addressing a state-of-the-art, multidisciplinary box, this ebook studies nanomaterials and their biomedical purposes. It covers regeneration, implants, adhesives, and biosensors and techniques for extra effective treatment, analysis, and drug supply with using nanotechnology.

• Addresses the expanding call for for nanomedicine in a state-of-the-art, multidisciplinary field
• Introduces options, options, and necessities of constructing materials
• Discusses scorching issues in drug supply, equivalent to neural regeneration, cartilage regeneration, bone tissue regeneration, dental regeneration, biomedical imaging, tissue adhesives and biosensors
• Includes a bankruptcy approximately nanotoxicology to assist readers additional comprehend the biocompatability of nanomaterials

Show description

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2008). Arginine‐chitosan/ DNA self‐assemble nanoparticles for gene delivery: in vitro characteristics and transfection efficiency. International Journal of Pharmaceutics 359, 241–246. , and Zhang, S. (2010). Slow and sustained release of active cytokines from self‐assembling peptide scaffolds. Journal of Controlled Release 145, 231–239. ‐C. (2000). Application to a cartilage targeting strategy: synthesis and in vivo biodistribution of 14C‐ labeled quaternary ammonium‐glucosamine conjugates. Bioconjugate Chemistry 11, 212–218.

The third type of CNS inhibitory molecules includes axon guidance mol­ ecules semaphorin and ephrin. Having a role in network stabilization by limiting neurite outgrowth, most semaphorins are inhibitory for n­ eurons. In the glial scar, class 3 semaphorins (Sema3s) contribute to the inhibitory environment in a CSPG‐dependent manner. Interfering CSPG–Sema3 inter­ action eliminates the inhibitory nature of this molecule in vitro (Pasterkamp and Verhaagen, 2006). , 2003). Ephrins exert their inhibitory effect by binding to EphA and EphB receptor tyrosine kinase on neural cell surface.

Pharmaceutical Research 28, 1843–1858. , and Nair, M. (2013). Targeted brain derived neurotrophic factors (BDNF) delivery across the blood‐brain barrier for neuro‐protection using magnetic nano carriers: an in‐vitro study. PLoS One 8, e62241. J. (2014). Aggrecan‐mimetic, ­glycosaminoglycan‐containing nanoparticles for growth factor stabilization and delivery. Biomacromolecules 15, 680–689. , and Domenech, J. (2007). The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.

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