This new source on handling oncologic emergencies is directed in any respect overall healthiness care execs who deal with sufferers with melanoma or survivors. Edited and written by means of clinician-experts on the college of Texas MD Anderson melanoma middle, the ebook covers the entire diversity of oncologic emergencies, from cardiac and neurologic to orthopedic to hematologic, and addresses very important palliative care, moral, and Emergency division considerations.
Chapters are established with busy clinicians in emergent and pressing settings in brain, and every bankruptcy concludes with a sequence of key perform issues and a listing of instructed readings in the event you desire to delve deeper right into a subject.
For any clinician dealing with the expanding variety of sufferers who adventure an oncologic emergency, this is often an up to date, clinically targeted, and authoritative source.
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Additional info for Oncologic Emergencies (MD Anderson Cancer Care Series)
Attention should be paid to phosphate binding. Hypercalcemia Hypercalcemia of malignancy is observed in 10–15 % of cancer patients. It is a poor prognostic sign that is associated with short survival durations. Clinical Manifestation Patients with mild hypercalcemia (calcium level less than 12 mg/dL) usually have no symptoms, whereas those with moderate or severe hypercalcemia are frequently symptomatic. Central nervous system symptoms are lethargy, ataxia, stupor, coma, mental status changes, and psychosis.
Acquired nephrogenic DI can result from the nephrotoxicity of drugs. Common nephrogenic DI-inducing drugs are lithium, foscarnet, and clozapine. Although distal tubular defects develop in about half of patients given ifosfamide, nephrogenic DI leading to hypernatremia is uncommon in them. In cancer patients, inadequate water intake can have many causes, including obstruction of the gastrointestinal tract, chemotherapy-induced nausea and vomiting, and chemotherapy- or radiotherapy-induced mucositis.
Hydrate with intravenous crystalloid fluid. 1 U/kg/h. The amount of insulin required for treatment of hyperosmolar hyperglycemic coma may be less than that required for diabetic ketoacidosis. 2 Metabolic and Endocrine Oncologic Emergencies 41 Hypoglycemia Hypoglycemia is defined as a blood glucose level less than 50 mg/dL. The timing of symptoms relative to a fasting or postprandial state can distinguish among various etiologies. Clinical Manifestations A progressive pattern of responses to hypoglycemia is determined by the availability of glucose to the brain.