Elastic Fiber Matrices: Biomimetic Approaches to by Anand Ramamurthi, Chandrasekhar Kothapalli

By Anand Ramamurthi, Chandrasekhar Kothapalli

Elastic Fiber Matrices: Biomimetic ways to Regeneration and Repair offers a complete source at the intrinsic and pathological aberrations of the advanced strategy of elastic matrix meeting and/or adaptations thereof in numerous elastic tissue varieties, and on techniques to regenerate or repair misplaced elastin matrix, both in vitro or in vivo, together with biomimetic elastin-like-peptides, gene treatment, drug supply, tissue engineering (biomolecules, scaffolds, and mechanical stimuli), pharmacological ways, elastin stabilization and protection, stem mobilephone remedy, allografts/xenografts, and synthetic/biological elastomers.

Comprised of person chapters contributed through top researchers and scientists within the box, the textual content information present techniques for elastin matrix regeneration and service, opting for their a variety of merits and obstacles whereas delivering priceless perception into rising tendencies. therefore, this ebook is a must have consultant for academicians and pros operating within the components of connective tissue biology, tissue engineering, dermal and cardiovascular biomaterials, and drug delivery.

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By Anand Ramamurthi, Chandrasekhar Kothapalli

Elastic Fiber Matrices: Biomimetic ways to Regeneration and Repair offers a complete source at the intrinsic and pathological aberrations of the advanced strategy of elastic matrix meeting and/or adaptations thereof in numerous elastic tissue varieties, and on techniques to regenerate or repair misplaced elastin matrix, both in vitro or in vivo, together with biomimetic elastin-like-peptides, gene treatment, drug supply, tissue engineering (biomolecules, scaffolds, and mechanical stimuli), pharmacological ways, elastin stabilization and protection, stem mobilephone remedy, allografts/xenografts, and synthetic/biological elastomers.

Comprised of person chapters contributed through top researchers and scientists within the box, the textual content information present techniques for elastin matrix regeneration and service, opting for their a variety of merits and obstacles whereas delivering priceless perception into rising tendencies. therefore, this ebook is a must have consultant for academicians and pros operating within the components of connective tissue biology, tissue engineering, dermal and cardiovascular biomaterials, and drug delivery.

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2014). 1 (Continued) The alveoli are saccular units at the end of each airway. Elastic fibers create rings at the entrance to each alveolus (middle panel, red). The right panel shows an image of baboon lung stained with Hart’s elastic fiber stain (brown) and tartrazine (yellow). Elastic fibers at the alveolar tips are dark in color (circled). (Reprinted and modified by permission from Macmillan Publishers Ltd. A. , 2007, Retinoids increase lung elastin expression but fail to alter morphology or angiogenesis genes in premature ventilated baboons.

Ryan. 1983. Elastin production by cultured calf pulmonary artery endothelial cells. J Cell Physiol 116(3): 282–288. , H. Hamagami, J. Shikata, and T. Yamamuro. 1986. Elastin in the human intervertebral disk. A histological and biochemical study comparing it with elastin in the human yellow ligament. Arch Orthop Trauma Surg 105(6): 343–349. Milewicz, D. , J. Grossfield, S. N. Cao et al. 1995. A mutation in FBN1 disrupts profibrillin processing and results in isolated skeletal features of the Marfan syndrome.

Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kgamma pathway. Cardiovasc Res 102(1): 118–127. Gerber, G. E. and R. A. Anwar. 1974. Structural studies on cross-linked regions of elastin. J Biol Chem 249(16): 5200–5207. Gibson, M. , G. Hatzinikolas, J. S. Kumaratilake et al. 1996. Further characterization of proteins associated with elastic fiber microfibrils including the molecular cloning of MAGP-2 (MP25). J Biol Chem 271(2): 1096–1103. Gibson, M. , J. S. Kumaratilake, and E.

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