Biomaterials for Musculoskeletal Regeneration: Concepts by Bikramjit Basu

By Bikramjit Basu

This booklet covers the fundamentals of the biomaterials technological know-how its purposes to bone tissue engineering. The introductory part describes the main invaluable techniques and strategies regarding the mobile and molecular biology with a specific specialize in comparing the biocompatibility estate. The structure of this booklet enables more straightforward knowing of the realm of bone tissue engineering. The ebook integrates the fabrics technology and organic technological know-how. It covers processing and simple fabric homes of assorted biocompatible metals and ceramics-based fabrics, in vitro and in vivo biocompatibility and toxicity evaluation within the context of bone tissue engineering, and processing and homes of metal-, ceramic- and polymer-based biocomposites, together with the fabrication of porous scaffold fabrics. The booklet can be utilized as a textbook for senior undergraduate and graduate coursework. it's going to even be an invaluable reference for researchers and pros operating within the area.

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By Bikramjit Basu

This booklet covers the fundamentals of the biomaterials technological know-how its purposes to bone tissue engineering. The introductory part describes the main invaluable techniques and strategies regarding the mobile and molecular biology with a specific specialize in comparing the biocompatibility estate. The structure of this booklet enables more straightforward knowing of the realm of bone tissue engineering. The ebook integrates the fabrics technology and organic technological know-how. It covers processing and simple fabric homes of assorted biocompatible metals and ceramics-based fabrics, in vitro and in vivo biocompatibility and toxicity evaluation within the context of bone tissue engineering, and processing and homes of metal-, ceramic- and polymer-based biocomposites, together with the fabrication of porous scaffold fabrics. The booklet can be utilized as a textbook for senior undergraduate and graduate coursework. it's going to even be an invaluable reference for researchers and pros operating within the area.

Show description

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Extra resources for Biomaterials for Musculoskeletal Regeneration: Concepts

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All these properties together make them ideal for biomedical applications. For example, hydroxyapatite, bioglasses, calcium phosphates, alumina and zirconia are used in dental and bone implant applications. However, ceramics have low fracture toughness (resistance to crack propagation), which limits their applications severely. Among all the ceramics, non-stoichiometric hydroxyapatite is of biological origin and is the major inorganic phase constituent of natural bone. Often in literature, ceramics, naturally available in living systems are termed as bioceramics, which are distinctly different from synthetic ceramics, synthesized outside human body but for use in biomedical applications.

12(5), 1197–1211 (2006) 20. : Bioprosthetic heart valve failure: pathology and pathogenesis. Cardiol. Clin. 2(4), 717–739 (1984) 21. : A comparison of endosseous dental implant surfaces. J. Periodontol. 70(12), 1523–1539 (1999) 22. : The effect of operative fit and hydroxyapatite coating on the mechanical and biological response to porous implants. J. Bone Joint Surg. 77(1), 97–110 (1995) 23. : Effect of hydroxyapatite impregnation on skeletal bonding of porous coated implants. J. Biomed. Mater.

Also, the ethical issues related to pre-clinical and clinical trials are emphasized. Keywords Animal experiments, Animal model, Apoptosis, Assay, Biocompatibility, Biodegradable polymer, Biomedical device, Blood, Bone tissue engineering, Cell functionality, Cell proliferation, Cell receptor, Cell viability, Cell-material interaction, Clinical trial, Comet assay, Critical-size defect, Cytocompatibility, Cytokine, Defect model, DNA damage, Engineering design, Ethical guideline, FACS, Femoral defect, Fibroblast cells, Flow cytometry, Gene expression, Genotoxicity, Goat model, HA, Hematoxylin and Eosin, Histology, Host response, in vitro, in vivo, LDH assay, Masson’s trichrome, Micro-CT, Micronucleus assay, MTT assay, Mullite, Necrosis, Osteoblast cells, Osteochondral defect, PLGA, Pre-clinical study, Programmed cell death, Rabbit model, Randomized control trial, Segmental defect, Substrate stiffness, Thrombus, Ti, Tissue compatibility, Toxicity, WST-1 assay, X-ray radiography, ZnO.

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